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Universitas Hasanuddin
Research output:Contribution to journal›Article›peer-review
Exploring the Cytotoxic Activity of Dillenia serrata Thunb. Leaf Extracts: An In Vitro and In Silico Investigation
Rasyid H.
Asian Pacific Journal of Cancer Prevention
Q2Published: 2025Citations: 1
Abstract
All extracts demonstrated intense toxicity levels. Out of all the extracts, ethyl acetate extract exhibited the strongest cytotoxic properties to HeLa cell lines with IC50 value 91.08±0.23 μg/mL. Ethyl acetate extract of D. serrata T. contains Phytol compounds which have a quite good affinity to the EGFR. According to this study, ethyl acetate extract has the potential to be used as an alternative to anticancer medication.
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10.31557/APJCP.2025.26.3.1043Other files and links
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