# Enteric fever in endemic areas of Indonesia: An increasing problem of resistance > Hatta M. URL kanonis: https://discover.unhas.ac.id/publications/enteric-fever-in-endemic-areas-of-indonesia-an-increasing-problem-of-resistance Jurnal / Konferensi: Journal of Infection in Developing Countries Tahun terbit: 2008 DOI: https://doi.org/10.3855/jidc.222 ISSN: 20366590 Kuartil SJR: Q3 Citations: 20 ## Authors - Hatta M. ## Abstract Reported levels of antibiotic resistance in Salmonella Typhi from South Sulawesi, Indonesia were very low (< 1%) before 2001 and chloramphenicol remained the treatment of choice. Since 2001 however resistance has been rising and in 2007 6.8% of isolates were resistant to all three first line drugs: Ampicillin, chloramphenicol and co-trimoxazole. Ciprofloxacin resistance is currently at 3.90 %. At the same time there has been an increase in the number of reported cases. This may be because of improved diagnostics or it may be a genuine outbreak of drug resistant S. Typhi. In conclusion drug resistant typhoid fever will become a serious problem in Indonesia in the future, requiring the use of expensive drugs for the treatment of typhoid. A concerted effort is needed by the medical services to implement reliable diagnosis so that treatment or vaccination can be used to control the spread of drug resistant typhoid fever. ## Keywords - Typhoid fever - Chloramphenicol - Ampicillin - Salmonella typhi - Ciprofloxacin - Medicine - Outbreak - Drug resistance - Virology - Antibiotics - Salmonella - Antibiotic resistance - Intensive care medicine - Microbiology - Biology - Bacteria - Genetics - Biochemistry - Gene - Escherichia coli --- Sumber: Discover Unhas — RIMS Universitas Hasanuddin. Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.