# Elucidating the role of APOE ε4 gene variants in the clinical manifestation of Parkinson's disease
> Soraya G.V.

URL kanonis: https://discover.unhas.ac.id/publications/elucidating-the-role-of-apoe-4-gene-variants-in-the-clinical-manifestation-of-pa
Jurnal / Konferensi: Frontiers in Aging Neuroscience
Tahun terbit: 2025
DOI: https://doi.org/10.3389/fnagi.2025.1632480
ISSN: 16634365
Kuartil SJR: Q1
Citations: 1

## Authors
- Soraya G.V.

## Abstract
The APOE ε4 allele is common in this preliminary study of 3 PD subjects. Our meta-analysis revealed a significantly earlier age-of-onset among APOE ε4 carriers relative to non-carriers, but no difference in disease severity and MMSE scores.

## Keywords
- Apolipoprotein E
- Disease
- Allele
- Gene
- Medicine
- Genetics
- Genetic variants
- Pathogenesis
- Biology
- Immunology
- Degenerative disease
- Polymorphism (computer science)
- Allele frequency
- Bioinformatics
- Genotype
- Significant difference
- Gene expression
- Internal medicine
- Case-control study
- Alzheimer's disease

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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