Effectivity of gambir extract (uncaria gambir roxb.) on the growth of bacteria staphylococcus aureus

Abstract

Objective: This study aims to see the Minimum Inhibitory Concentration (MIC), minimum contact time of gambir extract, and the effectiveness of gambir extract (Uncaria gambir Roxb.) on the inhibition of growth of Staphylococcus aureus bacteria. Material and Methods: This research is an experimental laboratory research. The research design used was the pre-test post-test control group. The samples used in the study were Staphylococcus aureus smear, gambir extract with the concentration of 2%, 4%, 6%, positive control (Chresophene), and negative control (aqubidest). Wilcoxon test and Mann Whitney test was used as the data analysis. Results: The study showed that the Minimum Inhibitory Concentration of gambir extract at the concentration of 2% and the inhibitory of gambir extract at the concentration of 2%, 4%, 6%, and aquabides against the growth of Staphylococcus aureus bacteria with a diameter of the inhibitory zone formed around the disc paper was 6.46mm, 6.64mm, 7.16mm, and 5.60mm within 24 hours while 6.57mm, 6.95mm, 7.54mm, and 5.60mm was formed within 48 hours. Conclusion: The MIC of gambir extract to Staphylococcus aureus is 2%, minimum contact time is 24 hours, and moderate inhibitory to Staphylococcus aureus bacteria.

Access to Document

Other files and links

• Link to publication in Scopus
• Open Access Version Available

Fingerprint