# Effect of artificial carbon dioxide-rich water immersion on peripheral blood flow in healthy volunteers: Preliminary study about artificial carbon dioxide-rich water > Hasyar A.R.A. URL kanonis: https://discover.unhas.ac.id/publications/effect-of-artificial-carbon-dioxide-rich-water-immersion-on-peripheral-blood-flo Jurnal / Konferensi: Open Access Macedonian Journal of Medical Sciences Tahun terbit: 2021 DOI: https://doi.org/10.3889/oamjms.2021.6591 ISSN: 18579655 Citations: 2 ## Authors - Hasyar A.R.A. ## Abstract BACKGROUND: Peripheral blood circulation disorder is one of the global health problems. Balneotherapy that uses CO2 springs may be one of the complementary treatment options. The device to produce artificial CO2-rich water is needed to achieve an improvement effect, at least almost like the improvement effect of natural balneotherapy. AIM: This study aims to investigate the effect of artificial CO2-rich water immersion on peripheral blood flow using Bicarbonated JesC CREA BC-2000. METHODS AND MATERIALS: Thirty-nine healthy volunteers participated in this study. Each subject immersed both of their legs in a mixed solution from water and CO2 at temperature 38°C. This solution was mixed using a device, namely, “Bicarbonated JesC CREA BC-2000”. Peripheral blood flow was measured for 5 min before immersion (in this study, we denoted it as the mean basal blood flow), 10 min during immersion, and 5 min after immersion using pocket JMS laser Doppler flowmetry MBF-IIA. Repeated analysis of variance was used for statistical analysis. RESULTS: There is the difference in peripheral blood flow among before, during, and after immersing the legs into artificial CO2-rich water using Bicarbonated JesC CREA BC-2000 (p < 0.001). CONCLUSION: Bicarbonated JesC CREA BC-2000 may be used as the device to produce an artificial CO2-rich water bath that may affect peripheral blood flow in healthy volunteers. ## Keywords - Medicine - Balneotherapy - Immersion (mathematics) - Blood flow - Carbon dioxide - Peripheral - Peripheral blood - Analysis of variance - Anesthesia - Biomedical engineering - Animal science - Surgery - Internal medicine - Pathology - Pure mathematics - Biology - Ecology - Mathematics - Alternative medicine --- Sumber: Discover Unhas — RIMS Universitas Hasanuddin. Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.