# Differences between several atherogenic parameters in patients with controlled and uncontrolled type 2 diabetes mellitus
> Susanti E.

URL kanonis: https://discover.unhas.ac.id/publications/differences-between-several-atherogenic-parameters-in-patients-with-controlled-a
Jurnal / Konferensi: Medical Journal of Indonesia
Tahun terbit: 2010
DOI: https://doi.org/10.13181/mji.v19i2.392
ISSN: 08531773
Kuartil SJR: Q4
Citations: 11

## Authors
- Susanti E.

## Abstract
Aim to assess the differences between Atherogenic Index of Plasma (AIP), ratio of oxidized-Low Density Lipoprotein (Ox-LDL)/High Density Lipoprotein (HDL) and ratio of Lipoprotein-associated Phospholipase A2 (Lp-PLA2)/HDL in predicting the risk of coronary heart disease (CHD) in patients with controlled and uncontrolled type 2 Diabetes Mellitus (T2DM). Methods The study was done observationally with cross sectional design. A total of 80 patients, consisted of 40 controlled and 40 uncontrolled T2DM. The serum triglyceride (TG), HDL-C, Ox-LDL, Lp-PLA2 were examined in their relationship with T2DM risk. AIP is a ratio calculated as log (TG/HDL-C). Results AIP and ratio of Ox-LDL/HDL were significantly higher in uncontrolled than controlled T2DM (0.72 ± 0.13 vs 0.47 ± 0.22 , p < 0.001) and (1738.8 ± 625.5 vs 1418 ± 535.3, p = 0.02), but no significant difference was found in ratio of Lp-PLA2/HDL (5.09 ± 2.17 vs 5.95 ± 3.11, p = 0.16). Conclusion AIP and ratio of Ox-LDL/HDL value were significantly higher in uncontrolled than in controlled T2DM. These parameters may be beneficial in predicting the risk of atherosclerosis in diabetic patients. (Med J Indones 2010; 19:103-8)  

## Keywords
- Internal medicine
- Type 2 Diabetes Mellitus
- Medicine
- Diabetes mellitus
- Endocrinology

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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