Diagnosis and management of central giant cell granulomas of the jaws: a European and multicenter study

Abstract

Further genetic and molecular studies regarding the pathways underlying CGCGs are needed, in order to predict their natural history and to direct non-surgical therapies. In the meantime, surgeons should balance the risks of higher recurrence rates associated with lower surgical morbidity, performing an individualized treatment plan, taking into consideration the clinical and radiological features together with the patients' age and comorbidities. A radiographic follow-up of patients with treated CGCGs could advised for the first 5 years.

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