# Dengue antiviral activity of polar extract from Melochia umbellata (Houtt) Stapf var. Visenia
> Soekamto N.H.

URL kanonis: https://discover.unhas.ac.id/publications/dengue-antiviral-activity-of-polar-extract-from-melochia-umbellata-houtt-stapf-v
Jurnal / Konferensi: Journal of Physics Conference Series
Tahun terbit: 2018
DOI: https://doi.org/10.1088/1742-6596/979/1/012017
ISSN: 17426588
Citations: 8

## Authors
- Soekamto N.H.

## Abstract
A research on the dengue antiviral activity test on the polar bark extract of M. umbelatta (Houtt.) Stapf var. Vicenia have been done to determine the relation to its activity againts brine shrimp Artemia salina. The bark was extracted by maceration with n-hexane, chloroform, and ethylacetate. The activity of the ethyl acetate extract was then tested against A. salina and dengue virus. It was found that the ethyl acetate extract was active to A. salina with the LC50 value of 101.66 μg/mL and also very active to dengue virus with the IC50 value of 1.67μg/mL. It is clear that the toxicity to brine shrimp A. salina has a positive correlation with the dengue anti virus.

## Keywords
- Brine shrimp
- Artemia salina
- Traditional medicine
- Dengue fever
- Dengue virus
- Ethyl acetate
- Maceration (sewage)
- IC50
- Chloroform
- Chemistry
- Bark (sound)
- Acute toxicity
- Biology
- Toxicity
- Chromatography
- In vitro
- Biochemistry
- Virology
- Medicine
- Organic chemistry
- Ecology
- Materials science
- Composite material

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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