# Correlation Phenolic Concentration to Antioxidant and Antibacterial Activities of Several Ethanolic extracts from Indonesia
> Sartini S.

URL kanonis: https://discover.unhas.ac.id/publications/correlation-phenolic-concentration-to-antioxidant-and-antibacterial-activities-o
Jurnal / Konferensi: Journal of Physics Conference Series
Tahun terbit: 2019
DOI: https://doi.org/10.1088/1742-6596/1341/7/072009
ISSN: 17426588
Citations: 15

## Authors
- Sartini S.

## Abstract
Abstract Increasing concerns on the adverse effect of synthetic antioxidants and the emergence of antibiotic-resistant Staphylococcus aureus have become two essential problems to be addressed. To tackle them, exploration of natural resources to discover novel antioxidants and/or antibacterial agents is urgently required. The aim of this research was to investigate the correlation of phenolic and flavonoid contents of extracts to their antioxidant and antibacterial activities. Green tea, green coffee, cocoa pod husks, bee pollen, and rosella calyces were processed and subjected to 80% ethanol-based maceration procedure to obtain extracts with appropriate condition. Each extract was examined for its phenolic and flavonoid concentrations using the Folin–Ciocalteau method and the aluminum chloride colorimetric assay, respectively. Further analysis on the free-radical scavenging potential and antibacterial/antibiofilm activity against S. aureus were carried out. Samples were found to contain total phenolics (TP) and total flavonoids (TF) at different concentrations. The highest level of TP and TF was identified in green tea extract and corresponded to the lowest IC 50 against DPPH and the lowest MIC against S. aureus colonies or to their respective biofilm. In contrast, low amounts of TP and TF were found in cocoa pod husks and bee pollen which were further demonstrated high IC 50 and high MIC. Collectively, our results suggested the linear correlation of phenolic- and flavonoid contents to the antioxidant and antibacterial/antibiofilm activities of plant extracts. The higher the phenolics and flavonoids level, the better the antioxidant and antibacterial/antibiofilm activities obtained from the corresponding extracts.

## Keywords
- DPPH
- Flavonoid
- Chemistry
- Maceration (sewage)
- Antioxidant
- Antibacterial activity
- Food science
- Bee pollen
- Traditional medicine
- Staphylococcus aureus
- Botany
- Biology
- Biochemistry
- Bacteria
- Pollen
- Genetics
- Composite material
- Materials science
- Medicine

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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