# Correlation of Brain-Derived Neurotrophic Factor and Fugl-Meyer Score Changes after Telerehabilitation in Stroke
> Mubarak H.

URL kanonis: https://discover.unhas.ac.id/publications/correlation-of-brain-derived-neurotrophic-factor-and-fugl-meyer-score-changes-af
Jurnal / Konferensi: Journal of Modern Rehabilitation
Tahun terbit: 2025
DOI: https://doi.org/10.18502/jmr.v19i4.19775
ISSN: 2538385X
Kuartil SJR: Q4
Citations: 0

## Authors
- Mubarak H.

## Abstract
Introduction: Early post-stroke rehabilitation reduces disability and improves quality of life. However, limited access to rehabilitation facilities presents a significant challenge. Home-based telerehabilitation has emerged as a viable solution to reach distant stroke populations. Motor recovery relies on penumbral reorganization and restructuring. Brain-derived neurotrophic factor (BDNF) plays a crucial role in regulating synaptic plasticity. However, the impact of additional rehabilitation sessions on BDNF levels and motor function in post-stroke patients remains unexplored. Materials and Methods: A randomized controlled trial was conducted from June to September 2023, involving 50 patients with stroke. A medical history was assessed using a questionnaire, and motor function was evaluated using the Fugl-Meyer assessment (FMA). Blood samples were collected to measure BDNF levels. The intervention included prescribing home-based exercises using a telerehabilitation application on cell phones for 12 weeks. BDNF levels and FMA scores were reassessed at the end of the study. Results: Significant increases in BDNF and FMA scores were observed in the mobile-based telerehabilitation group. The increase in BDNF and FMA levels in the intervention group exceeded that of the control group. Conclusion: Mobile-based telerehabilitation is superior to conventional home exercise programs for delivering home-based therapeutic exercises

## Keywords
- Telerehabilitation
- Medicine
- Rehabilitation
- Physical medicine and rehabilitation
- Physical therapy
- Stroke (engine)
- Intervention (counseling)
- Quality of life (healthcare)
- Randomized controlled trial
- Neurotrophic factors
- Telemedicine
- Minimal clinically important difference
- Clinical trial
- Observational study
- Motor function

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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