Comparison of the effectiveness of transversus abdominis plane block with infiltration local anesthetic combination of intraoperative paracetamol as multimodal analgesia against pain intensity, first rescue opioid and interleukin-6 levels in postcesarean section patients with spinal anesthesia

Abstract

BACKGROUND: Surgical pain is a problem often faced by women after cesarean section. Cesarean section surgery can cause moderate to severe pain that lasts 48 hours after surgery. The aim of this study was to compare the effectiveness of transversus abdominis plane (TAP) block with local anesthetic infiltration combined intraoperative paracetamol as multimodal analgesia against pain intensity, first opioid rescue time and interleukin-6 (IL-6) levels in postcesarean section subjects with spinal anesthesia.METHODS: This study is a single blind randomized clinical trial (RCT) experimental study that aimed to analyze the comparative effectiveness of TAP with local anesthetic infiltration combined with intraoperative paracetamol as multimodal analgesia against pain intensity, first opioid rescue time and IL-6 levels in postcesarean section subjects with spinal anesthesia.RESULTS: In this study it was found a significant value >0.05 in comparison NRS to IL-6 in groups 1 and 2.CONCLUSIONS: There were significant differences in the effectiveness of TAP block with local anesthetic infiltration combined with intraoperative paracetamol as multimodal analgesia on pain intensity, first opioid rescue time and IL-6 levels in postcesarean section subjects with spinal anesthesia.

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