# Comparison of electronic cigarette smoke and conventional cigarette smoke exposure on brain histopathology and brainderived neurotrophic factor level
> Prabawati A.

URL kanonis: https://discover.unhas.ac.id/publications/comparison-of-electronic-cigarette-smoke-and-conventional-cigarette-smoke-exposu
Jurnal / Konferensi: Gaceta Medica De Caracas
Tahun terbit: 2025
DOI: https://doi.org/10.47307/GMC.2025.133.1.14
ISSN: 03674762
Kuartil SJR: Q4
Citations: 1

## Authors
- Prabawati A.

## Abstract
Objectives: This study aims to evaluate and compare the effects of exposure to electronic and conventional cigarette smoke on the levels of Brain-Derived Neurotrophic Factor (BDNF) and the histopathological features of the brain in rats. Methods: 24 male Wistar rats were divided into three groups: a control group (no exposure to cigarette smoke) and two experimental groups exposed to either regular cigarette smoke (1.8 mg nicotine, 32 mg tar, 25 minutes/day for 4 weeks) or e-cigarette aerosol (1.8 mg/mL nicotine solution, 30 minutes/day for 30 days). Result: The results indicate that the BDNF levels in the conventional cigarette group were 1.27 higher than the control group, showing a relatively small difference.

## Keywords
- Cigarette smoke
- Histopathology
- Smoke
- Medicine
- Brain-derived neurotrophic factor
- Neurotrophic factors
- Electronic cigarette
- Pathology
- Neuroscience
- Physiology
- Internal medicine
- Chemistry
- Biology
- Environmental health
- Organic chemistry
- Receptor

---
Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.