Comparative Efficacy of 2% Hyperbaric Prilocaine vs 0.5% Hyperbaric Bupivacaine in Spinal Anesthesia for Urologic Endoscopy Procedures

Abstract

Introduction. In the evolving landscape of anesthetic practices for short-duration urologic procedures, the quest for an anesthetic agent that balances efficacy with minimal side effects remains a significant clinical challenge. Addressing this need is crucial for improving patient outcomes and surgical efficiency. Objective. This study aims to compare the effectiveness and safety of 2% hyperbaric prilocaine with 0.5% hyperbaric bupivacaine in spinal anesthesia, specifically focusing on their application in urologic endoscopy. Material and methods. A comparative analysis was conducted between 2% hyperbaric prilocaine and 0.5% hyperbaric bupivacaine. The parameters evaluated included the onset and duration of sensory and motor block, incidence of side effects such as hypotension and bradycardia, and overall patient outcomes in urologic endoscopy. Results. The study found that prilocaine offers a faster onset of sensory and motor block and a shorter duration of sensory block compared to bupivacaine. Prilocaine also showed a quicker recovery of full motor function and had a significantly lower incidence of side effects, including hypotension and bradycardia. Conclusion. The findings suggest that 2% hyperbaric prilocaine could be a more efficient alternative to 0.5% hyperbaric bupivacaine in spinal anesthesia for urologic endoscopy, particularly for procedures requiring quick recovery and reduced side effects. This research highlights the potential for prilocaine to improve anesthetic practices not only in urologic endoscopy but also in other short-duration surgeries, promoting enhanced patient safety, comfort, and overall surgical care efficiency.

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