# Cloning and analysis of non-specific cytotoxic cell receptor (NCCRP)-1 from common carp Cyprinus carpio L.
> Sakata H.

URL kanonis: https://discover.unhas.ac.id/publications/cloning-and-analysis-of-non-specific-cytotoxic-cell-receptor-nccrp-1-from-common
Jurnal / Konferensi: Comparative Biochemistry and Physiology C Toxicology and Pharmacology
Tahun terbit: 2005
DOI: https://doi.org/10.1016/j.cca.2005.02.009
ISSN: 15320456
Kuartil SJR: Q1
Citations: 19

## Authors
- Sakata H.

## Abstract
Nonspecific cytotoxic cell receptor protein (NCCRP-1) provides an important function in target cell recognition and activation of cytotoxicity. NCCRP-1 has been cloned from common carp Cyprinus carpio L. from fish barbel by EST analysis. The isolated gene is composed of 945 bp with a 79 bp 5' UTR, 714 bp open reading frame and 152 bp 3' UTR. The predicted NCCRP-1 gene is composed of 237 amino acid residues and its predicted signal peptide is 19 amino acid residues in length. This gene has conservation of all the related domains characteristic to the NCCRP-1 gene in fish. Phylogenetic and genomic analyses showed that carp NCCRP-1 was similar to other fish orthologues. The expression of NCCRP-1 gene was constitutive in both lymphoid and non-lymphoid tissues. Furthermore, by semi-quantitative RT-PCR studies, we showed that NCCRP-1 gene expression is increased in anterior kidney challenged with Aeromonas hydrophila.

## Keywords
- Biology
- Common carp
- Carp
- Cyprinus
- Gene
- Open reading frame
- Molecular biology
- Cloning (programming)
- Barbel
- Genetics
- Peptide sequence
- Fishery
- Fish <Actinopterygii>
- Programming language
- Computer science

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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