# Chitosan from sea urchin (Diadema setosum) spines for orthodontic miniscrews: Antibacterial effects against key oral pathogens
> Mansjur K.Q.

URL kanonis: https://discover.unhas.ac.id/publications/chitosan-from-sea-urchin-diadema-setosum-spines-for-orthodontic-miniscrews-antib
Jurnal / Konferensi: Journal of Oral Biology and Craniofacial Research
Tahun terbit: 2025
DOI: https://doi.org/10.1016/j.jobcr.2025.02.014
ISSN: 22124268
Kuartil SJR: Q2
Citations: 3

## Authors
- Mansjur K.Q.

## Abstract
Sea urchin-derived chitosan demonstrated significant antibacterial effects against key oral pathogens associated with peri-implantitis, with minimum inhibitory concentrations (MICs) of 16 ppm against <i>Fusobacterium nucleatum</i> and 32 ppm for both <i>Aggregatibacter actinomycetemcomitans</i> and <i>Porphyromonas gingivalis</i>. The minimum bactericidal concentrations (MBCs) were 4 ppm for <i>A. actinomycetemcomitans</i> and 16 ppm for both <i>F. nucleatum</i> and <i>P. gingivalis,</i> indicating its strong bactericidal potential. Scanning electron microscopy (SEM) revealed that sea urchin chitosan effectively adhered to the surface of orthodontic miniscrews, showcasing its potential as a functional antimicrobial coating. These results emphasize the capability of sea urchin chitosan to target key oral pathogens, offering a promising approach to enhance microbial resistance and improve outcomes in orthodontic treatments.

## Keywords
- Sea urchin
- Chitosan
- Key (lock)
- Biology
- Dentistry
- Medicine
- Ecology
- Biochemistry

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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