CD4+ cell impacts of orally red fruit (Pandanus conoideus) oil extract in HIV patients with antiretroviral therapy

Abstract

Background and Objective: The efficacy of red fruit (Pandanus conoideus) oil extract on CD4+ cells was evaluated in HIV infected patients with taking antiretroviral therapy. Materials and Method: Seventy patients with an age of 17-45 years, with confirmed HIV infection with a CD4 count of 200-349 cells/ ?L, were divided into the antiretroviral (ARV) control (n = 35) and the antiretroviral + red fruit capsule (ARV+RFC)-treated (n = 35) groups. In ARV+RFC group, they were given oral RFC (1 g daily for two months). Monitoring evaluations of the laboratory were performed at baseline (0 months) and two months during the study. Results: The result showed that the CD4+ cells count was increased in the patient who took ARV+RFC compared with ARV alone (P<0.05). Conclusion: By these result, it can be concluded that the red fruit oil extract may have an excellent immunomodulatory impact and has potential as an adjuvant in the management of HIV patients

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