Antifungal activity of Cinnamomum iners bark extract against Schizophyllum commune

Abstract

Abstract Plants contain various bioactive compounds that benefit humans and the environment, such as antimicrobial, antiplasmodial, cytotoxic, amylase inhibitor, antinociceptive, anti-inflammatory, biopesticide, and antifungal. This study aims to analyze the antifungal activity of teja lawang ( Cinnamomum iners ) bark extract against the wood-decaying fungi Schizophyllum commune . The bark powder samples with a 40-60 mesh size came from three trees with a diameter of approximately 30 cm growing at the Forest Education of Hasanuddin University. The powder was extracted with methanol and acetone, followed by successive fractionation with n-hexane, ethyl acetate, and water. The effectiveness of antifungal activity was determined based on the Antifungal Activity (AFA) value, with testing patterned in a completely randomized design for six treatments at two concentrations, namely 50 ppm and 100 ppm. The results showed that acetone and methanol extract yields were 6.39% and 3.52%, respectively. Adding extract and its fractions to PDA media can inhibit the growth of S. commune with an AFA index ranging from 64% to 100%, categorized as strong to very strong. The C. iners bark extract has significant potential as a biocontrol agent for the fungus S. commune .

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