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Universitas Hasanuddin
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Anti-aging properties of the probiotic strain Lactobacillus plantarum ATCC 8014. Preliminary report

Utomo T.

Aesthetic Cosmetology and Medicine

Q3
Published: 2025

Abstract

Aging is a biological process that results in structural and functional changes in the skin, including wrinkles, reduced hydration, and imbalanced ceramide levels. This study evaluated the effectiveness of a topical serum probiotic containing Lactobacillus plantarum ATCC-8014 on wrinkle index, skin hydration, and ceramide levels. A pilot randomised controlled trial was conducted with 18 participants aged 30-60 years, assigned to either a treatment group using serum probiotics Lactobacillus plantarum or a control group using a serum with propylene glycol and glycerin. Promising improvements in wrinkle index, skin hydration, and ceramide levels were observed in the treatment group. These findings suggest that Lactobacillus plantarum may be a potential anti-aging agent.

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10.52336/acm.2025.012

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