Analysis of colorectal cancer survival rate at a single institution

Abstract

Currently, the prevalence of colorectal cancer (CRC) ranks among the top four diseases in the world. Indonesia ranks third in CRC, with poor survival rates. The high prevalence of CRC requires early diagnosis and intervention. This is expected to improve the survival rate of patients with CRC. The aim of this study was to compare the survival rate of patients based on age and pathological categories. This study was an observational, analytic study with a cross-sectional approach consisting of 470 patients diagnosed with colorectal cancer in our institution. Data was obtained from medical records, and univariate, bivariate, multivariate data analyses and survival analysis were performed. Most CRCs occur in the rectal area (41.3%). Those who experienced metastasis (25.8%) were mostly liver cancer patients, mostly in stage 3 (67.2%), with a moderate differentiation rate of 82.8 percent. This study proves that there is a significant difference between survival rates for age categories where age ≥ 50 years tends to have a lower survival rate (HR 1.6; p < 0.05). Survival rate is also influenced by differences in stadium (HR; 4.6; p < 0.05). This study shows that the survival rate for colorectal cancer patients at our institution is mostly <5 years. Age and pathology are the deciding factors in determining survival rates. Early diagnosis and immediate therapy are important steps in reducing mortality and morbidity.

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